As a cat owner, I never get tired of watching my furry friend go nuts rolling around and rubbing up against his catnip toys.
But why does catnip make cats go crazy? After doing some research on this funny feline phenomenon, I discovered the scientific reasons behind the catnip craze.
Let me tell you about the first time I gave my kitten catnip. As soon as he smelled the aromatic herb, his eyes went wide and he started excitedly bunny-kicking his back legs into the air! He rolled from side to side, batted the toy all over, and even drooled a bit – it was hilarious. This frisky reaction lasted about 10 minutes before he got tuckered out.
Clearly catnip triggers something in a cat’s brain that makes them go wild! The effect is entertaining for us owners, if a bit confusing. But scientists have actually identified the specific reasons catnip sends cats into a frenzy. Keep reading to learn about the chemical compounds, genetics, and instincts behind the catnip phenomenon. You’ll never look at this harmless herb the same way again!
KEY TAKEAWAY
Why does catnip make cats go crazy?
Catnip contains a chemical compound called nepetalactone (1), which stimulates certain receptors in a cat’s brain, leading to a range of behaviors such as rolling, rubbing, and jumping. This response is thought to be an inherited trait that affects about 50-75% of cats, and the effects of catnip are generally harmless and temporary.
The Enigmatic Effect of Catnip: Why Cats Go Crazy
Anyone who has given their cat catnip knows the bizarre, funny effects it seems to have on our feline friends. But why does this aromatic herb make cats go absolutely nuts, rolling, pouncing and rubbing ecstatically? The reasons behind the catnip reaction have long puzzled researchers.
When exposed to catnip, most domestic cats will sniff, lick and chew it intensely, rub up against it, vocalize, and play wildly—all signs of keyed up excitement. They may roll over, flip upside down, and even drool. The frenzied state typically lasts around 5-15 minutes before kitty loses interest.
Clearly catnip triggers something potent in a cat’s physiology and brain to elicit this intense response. As scientists have studied the plant further, they’ve uncovered the chemical secrets that make catnip tantalizing and maddening for cats. Let’s explore!
Decoding the Role of Nepetalactone in Catnip’s Effects

The magic ingredient in catnip that causes such crazy feline behavior is an organic compound called nepetalactone (2). This chemical compound binds to receptors in a cat’s nose and brain that trigger the characteristic euphoric state.
Nepetalactone is found in the highest concentrations in the buds and leaves of catnip plants. When sniffed, licked or eaten, it travels quickly to olfactory tissue and areas of the brain regulating pleasure and excitement.
For reasons not fully understood, nepetalactone does not have the same effect on humans or other mammals like dogs. Only in domestic and wild cats does it induce the frenzied reactions we associate with catnip toys and treats. A little nepetalactone goes a long way!
Now that researchers have identified nepetalactone as the active agent, we better understand how catnip hijacks kitty’s senses. But the fun doesn’t stop there…let’s dig into the sensory and genetic intricacies underlying this phenomenon.
Catnip’s Journey in a Cat’s Body: From Nose to Brain

When a cat encounters catnip, the nepetalactone molecules travel quickly from the nose to the brain to work their magic. Understanding this journey helps explain why cats get so crazed!
First, cats have an excellent sense of smell, with 200 million odor-sensitive cells compared to our 5 million. They easily detect nepetalactone particles on catnip. Inhaling brings the molecules in contact with these receptors.
Next, the molecules pass rapidly through nostrils to olfactory tissue containing neuron receptors specifically tuned to nepetalactone. The chemical binds to these receptors, signaling the euphoric reaction to the brain.
In the brain, nepetalactone stimulates areas governing pleasure, emotion, and behavioral instincts. This triggers the release of feel-good neurotransmitters like endorphins and dopamine, making kitty feel blissful and wild!
It’s this potent reaction from nose to brain that transforms calm kitties into catnip-crazed maniacs! Now let’s explore why only some cats react.
Genetic Quirks: Unraveling the Mystery of Catnip Responsiveness
If you’ve ever met a cat who couldn’t care less about catnip, you may be surprised to learn around 20-30% of cats are immune to its zany effects. The difference comes down to genetics.
See, nepetalactone binds to olfactory receptors passed down genetically. Some cats lack the specific receptor targeted by nepetalactone molecules, rendering catnip powerless. It simply can’t bind anywhere to trigger a reaction.
Breeding also plays a role. Persians, Bengals, Siamese, Maine Coons, and Ragdolls are especially susceptible. Shelter cats likely have mixed gene pools driving variability in responsiveness.
So next time you meet a cat who snoozes through a catnip party, don’t take it personally! Their lack of reaction is no fault of their own. They simply missed out on the catnip craze gene.
Sniffing vs. Eating: How Catnip Alters Feline Behavior
Cat owners often wonder if giving kitty catnip treats has the same effect as catnip-filled toys. It turns out sniffing versus eating catnip produces slightly different responses!
When smelled, catnip vapor molecules travel straight to olfactory receptors, triggering the excitable reactions we expect: rubbing, rolling, bunny-kicking. Eating, however, leads to more mellow, relaxed responses.
While cats still respond to nepetalactone through taste and digestion, the slower absorption makes them blissful rather than hyperactive. Some cats also don’t like the flavor.
So for the classic frenzied catnip fun, stick to toys and scented products. But catnip treats can also create enjoyable, if more subdued, experiences. Dosing method changes the response!
More on the origin of catnip.
Maximizing Enjoyment and Safety with Catnip Toys
While catnip is safe for feline playtime, some basic tips will keep your cat’s experience positive and prevent overstimulation:
- Use catnip in moderation, not daily. Limit to a few times weekly.
- Keep pet areas clean to prevent aggressive “highs.” Don’t use catnip if male cats are stressed.
- Store catnip tightly sealed and out of pets’ reach. Fresher herb has more nepetalactone.
- Try organic catnip to avoid pesticide residues. Avoid essential oils (toxic for cats).
- Monitor play and remove catnip if kitty seems overly aggressive or distressed.
With common sense precautions, catnip makes a fun occasional treat! Just be sure to keep your camera ready to capture the crazy catnip chaos.
More on is catnip safe for cats.
Conclusion
As we’ve discussed, catnip contains a chemical compound similar to feline pheromones which triggers a euphoric response when smelled. This explains the crazy rubbing, rolling, and running around cats display when exposed to catnip. Not all cats react, since the sensitivity depends on genetics.
While the catnip response may seem random, it’s simply your cat expressing its natural hunting instincts in a safe, stimulating way. The frenzy typically lasts 5-15 minutes before your kitty loses interest. It’s perfectly harmless fun!
Now that you understand the science behind the catnip craze, you can use these aromatic toys to provide your cat healthy excitement and enrichment. Just be sure to supervise use and offer catnip moderately as part of a balanced playtime routine. Enjoy the silly show!
More on how to make catnip.
References
- https://www.newscientist.com/article/2274319-science-with-sam-why-do-cats-go-crazy-for-catnip/#:~:text=The%20chemical%20responsible%20for%20messing,usually%20lasts%20around%2015%20minutes.
- https://en.wikipedia.org/wiki/Nepetalactone#:~:text=Nepetalactone%20is%20a%20name%20for,by%20functioning%20as%20insect%20repellents.